The Role of Maternal Hematological Conditions in the Incidence of Neonatal Jaundice
DOI:
https://doi.org/10.53366/jimki.v12i3.1069Keywords:
Keywords: Neonatal jaundice; maternal hematologic conditions; maternal risk factors.Abstract
Introduction: Neonatal jaundice is a common clinical condition that can progress to serious complications if left untreated. Several studies have shown that maternal hematological conditions play a significant role in influencing the risk of hyperbilirubinemia in neonates.
Methods: This literature review utilized six nationally and internationally indexed articles (2020–2025), selected through the PRISMA pathway, focusing on the association of maternal hematological factors with the incidence of neonatal jaundice.
Results: The reviewed studies identified several maternal hematological determinants, including elevated WBC and MCV, anemia, PROM, GDM, and ABO and Rh incompatibility, as contributing factors to an increased risk of hyperbilirubinemia. Obstetric factors such as maternal age, duration of labor, and maternal disease also strengthen this association.
Discussion: Maternal hematological conditions influence neonatal jaundice through mechanisms of hemolysis, inflammation, immunological disorders, and the fetus's metabolic inability to manage bilirubin. The interaction between maternal hematological status and obstetrical events exacerbates neonatal erythrocyte instability and increases bilirubin accumulation.
Conclusion: Maternal hematological status is an important determinant of neonatal jaundice, therefore, increased hematological monitoring in pregnant women is necessary as a preventive measure to reduce the risk of hyperbilirubinemia in newborns.
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